Prostatitis

Medications for Prostatitis

For nonbacterial prostatitis caused by Chlamydia and Ureaplasma species, which are difficult to culture, an empiric trial of doxycycline or erythromycin should be instituted.

For the treatment of chronic bacterial prostatitis, where Enterobacteriaceae, enterococci, and P aeruginosa are common pathogens, consider trimethoprim/sulfamethoxazole (Bactrim) or fluoroquinolones for 28 days or more as empiric agents.

Drug Category: Alpha-adrenergic antagonists

These agents are used in the treatment of benign prostatic hypertrophy.

Alpha-blockers may also have role in chronic pelvic pain syndrome to improve symptoms.

Studies suggest that combining alpha-blockers with antibiotics may reduce the risk of prostatitis recurrence in chronic prostatitis. Alpha-blockers improve bladder outlet obstruction and thus improves voiding dysfunction that may be associated with the pathogenesis of prostatitis.